The Osteoinductive Properties And Influence of “Emdogain” (Straumann) on Colony-Forming Properties of Human Osteogenous Progenitor Bone Marrow Cells Ex vivo

Abstract

Generalized periodontitis (GP) is widespread disease among working category of patients that is very actual for Ukraine where periodontology still is not recognized specialty. Modern data demonstrate presence of connection and influence of GP on development of chronic diseases that is very important point for general health care of citizens, especially of Ukraine. According to Biloklytska G., an effective treatment of GP for citizens of Ukraine is among priorities, where statistics of disease prevalence shows very high percent of patient`s involvement. Growing tendency among our patients revealed fact of great want of patients to leave natural tooth on place instead of extraction. This fact enforces practicing dentists to search for more favor and biology based treatment techniques of GP. Especially it is important during usage of additional materials and medications for periodontal regeneration. This means that all used modern materials should fulfill all the demands, especially when we deal with regenerative periodontology, when the periodontal regeneration highly expected. Usage of enamel matrix proteins in periodontology is still very perspective promoting periodontal regeneration, influencing on different parts of periodontal wound regeneration. Also the regeneration of bone tissue as component of periodontal complex can be enhanced due to biological mechanisms support. In the review the preliminary data about details of occurrence of osteoinductive properties of “Emdogain” (Straumann) and the influence on colony forming properties of osteongenous bone marrow cells will be showed. The preliminary results will be showed and discussed.