PATHOMORPHOLOGICAL FEATURES OF PULMONARY INJURIES IN GENERALIZED CRYPTOCOCCOSIS IN PATIENTS WITH HIV / AIDS

Abstract

The pathomorphological picture of lung lesions is polymorphic and represented by multiple foci of necrosis in some cases by an inflammatory reaction in the form of granulomatous inflammation and accumulation of cryptococci. The macroscopic picture is less specific, which necessitates not only routine histological but also histochemical diagnostic methods. The nature and severity of pathological changes depend on the state of the immune system, virulence, etiotropic therapy, as well as the duration and timeliness of diagnosis.