A clinical case of eosinophilic granulomatosis with polyangiitis manifestation with a tumor in the pericardium in combination with high titers of serum immunoglobulin G4

Abstract

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic disease which is histopathologically characterized by eosinophilic infiltration, extravascular granulomas and necrotizing vasculitis with predominantly small and medium vascular involvement. An accurate diagnosis of EGPA is often difficult due to clinical manifestations similar or overlapping with chronic eosinophilic pneumonia, hypereosinophilic syndrome, other primary systemic vasculitis, and hyperimmunoglobulin G4 syndrome.