Применение оригинального продукта на растительной основе Синудафен в лечении детей разного возраста с острым риносинуситом: результаты открытого сравнительного обсервационного исследования

Abstract

Introduction. According to studies by various authors, acute rhinosinusitis (ARS) affects from 6% to 15% of the world’s population. The tactics of ARS treatment depends on the localization of the process, degree of dysfunction of the anastomosis of the paranasal sinuses, phenotypic features of the ARS course, in particular, the nature of the inflammatory process and presence of complications. Purpose. To study the effectiveness of use of the plant-based dietary supplement Sinudafen in the complex treatment of children with ARS from 3 to 12 years old. Materials and methods. The study was carried out according to the approved protocol and informed consent of parents at two clinical sites: the ENT department of the National Children’s Specialized Hospital “OKHMATDYT” (Kyiv) and the infectious diseases departments of the ONP “Chernivtsi Regional Children’s Hospital” (Chernivtsi). We observed 80 patients with ARS at the age from 3 to 12 years. The main group consisted of 60 patients, who received the plant-based dietary supplement Sinudafen, the control group – 20 children receiving basic therapy. Results. Researchers of the two clinical centers independently concluded that the use of the plant- based dietary supplement Sinudafen in the complex treatment of children with ARS at the age from 3 to 12 years helps to reduce local (hyperemia and edema of the nasal mucosa, rhinorrhea, difficulty in nasal breathing) and general (headache, general weakness, fever, lacrimation, sneezing) manifestations of ARS in a shorter time if compared to the control group. Conclusion. Thus, the obtained results indicate the efficacy and safety of the plant-based dietary supplement Sinudafen in the treatment of acute rhinosinusitis in children aged from 3 to 12 years, which makes it possible to recommend it for widespread use in acute upper respiratory tract infections.