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http://lib.inmeds.com.ua:8080/jspui/handle/lib/3402
Назва: | Insulin Resistance Syndrome Associated with Subclinical Hypothyroidism in Postmenopausal Women |
Автори: | Жердьова, Н.М. |
Ключові слова: | hypothyroidism, insulin resistance |
Дата публікації: | тра-2021 |
Видавництво: | Metabolism |
Короткий огляд (реферат): | Backgroud: Postmenopausal women are known to have a higher prevalence of the insulin resistance (IR) syndrome and subclinical hypothyroidism (SH). A major component of the IR syndrome is associated with type 2 diabetes mellitus, non-alcoholic fatty liver disease (NAFDL), dyslipidemia, obesity, hypertension in postmenopausal women. Objective: The present study aims to assess symptoms of IR syndrome and SH in postmenopausal women. Methods: A total of 54 postmenopausal women have been examined and divided into 2 groups. Group I: 24 postmenopausal women with IR syndrome. Group II: 30 postmenopausal women with IR syndrome and SH. All subjects were clinically examined and evaluated for thyroid stimulation hormone (TSH), free thyroxine, HOMA-IR, fasting glycaemia, lipid metabolism. Thyroid and liver ultrasonography were performed with Doppler mode. Results: Thyroid ultrasound showed total thyroid volume of 12, 30±1,40 cm3 in 57% of patients with IR syndrome and SH and 9,50±1,22 cm3 in the group I. Liver ultrasonography showed hepatosis were present in 95% of postmenopausal women in group II and 90% in the group I. In the group I in 60% of females has dyslipidemia and 98% patients IR (pb0.001). The patients of the group II had 95% IR and all women dyslipidemia (pb0.001). Conclusion: this demonstrates that SH is frequent in patients with IR syndrome and indicates a potential cardiovascular risk due to the association of subclinical hypothyroidism, dislipidemia and suggests that NAFLD in postmenopausal women should be screened for thyroid function |
URI (Уніфікований ідентифікатор ресурсу): | http://lib.inmeds.com.ua:8080/jspui/handle/lib/3402 |
Розташовується у зібраннях: | Кафедра діабетології |
Файли цього матеріалу:
Файл | Опис | Розмір | Формат | |
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0050.InsulinResistanceSyndromeAssociatedwithSubclinicalHypothyroidisminPostmenopausalWomen.pdf | 110.37 kB | Adobe PDF | Переглянути/Відкрити |
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