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dc.contributor.authorКосаковський, Анатолій Лук'янович-
dc.contributor.authorPalm, Jürgen-
dc.contributor.authorKishchuk, Vasyl V.-
dc.contributor.authorKosakovskyi, Anatolii-
dc.contributor.authorMityuryayeva-Korniiko, Inga-
dc.contributor.authorPukhlik, Sergiy M.-
dc.contributor.authorTretiakevych, Zoia-
dc.contributor.author....-
dc.date.accessioned2020-11-24T20:35:06Z-
dc.date.available2020-11-24T20:35:06Z-
dc.date.issued2017-
dc.identifier.urihttp://lib.inmeds.com.ua:8080/jspui/handle/lib/2556-
dc.description.abstractObjective: To investigate the effectiveness and safety of the homeopathic product SilAtro-5-90 in recurrent tonsillitis. Methods: In this international, pragmatic, controlled clinical trial, 256 patients (6e60 years) with moderate recurrent tonsillitis were randomized to receive either SilAtro-5-90 in addition to standard symptomatic treatment, or to receive standard treatment only. The primary outcome was the mean time period between consecutive acute throat infections (ATI) within 1 year (analyzed via repeated events analysis). Results: During the evaluation year, the risk of getting an ATI was significantly lower (hazard ratio: 0.45, proportional means model, p 1⁄4 0.0002, ITT) with SilAtro-5-90 compared to control. Tonsillitis-specific symptoms were significantly reduced (p < 0.0001, ITT) and the need of antibiotics to treat acute throat infections (p 1⁄4 0.0008; ITT) decreased. 3 non-serious adverse drug reactions were reported for SilAtro-5-90. Conclusions: An integrative treatment approach where SilAtro-5-90 is given alongside mainstream symptomatic treatment may bring therapeutic benefit to patients suffering from recurrent tonsillitis. Trial registration: ISRCTN registry: Registration number ISRCTN19016626, registered 23 January 2013. © 2017 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).uk_UK
dc.language.isoenuk_UK
dc.publisherComplementary Therapies in Clinical Practice 28 (2017) 181e191uk_UK
dc.subjectHomeopathy Recurrent tonsillitis Tonsilotren SilAtro-5-90 Acute throat infection Randomized controlled trialuk_UK
dc.titleEffectiveness of an add-on treatment with the homeopathic medication SilAtro-5-90 in recurrent tonsillitis: An international, pragmatic, randomized, controlled clinical trialuk_UK
dc.typeArticleuk_UK
Розташовується у зібраннях:Кафедра дитячої оториноларингології, аудіології та фоніатрії

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