DSpace Community:http://localhost:8080/jspui/handle/lib/1122024-02-25T02:45:26Z2024-02-25T02:45:26ZОцінка виразності больового синдрому та шляхи його усунення в пацієнтів із синдромом подразненого кишечникаАнохіна, Галина АнатоліївнаХарченко, Вячеслав ВікторовичЛопух, Ігор ЯрославовичКоруля, Ірина Анатоліївнаhttp://localhost:8080/jspui/handle/lib/48312024-01-03T09:53:46Z2023-01-01T00:00:00ZTitle: Оцінка виразності больового синдрому та шляхи його усунення в пацієнтів із синдромом подразненого кишечника
Authors: Анохіна, Галина Анатоліївна; Харченко, Вячеслав Вікторович; Лопух, Ігор Ярославович; Коруля, Ірина Анатоліївна
Abstract: Комплексне лікування із застосуванням персоніфікованих дієтичних рекомендацій, синтетичного агоніста периферичних опіоїдних рецепторів тримебутину малеату та синбіотика, до складу
якого входять Lactobacillus acidophilus, L. rhamnosus, Sacchromyces boulardii, Bifidobacterium lactis,
B. longum, Clostridium butyricum, Bacillus clausii spores, Fructo oligosaccharides, сприяло зменшенню виразності больового синдрому, поліпшенню психоемоційного стану та якості життя пацієнтів.2023-01-01T00:00:00ZКлінічні рекомендації Української гастроентерологічної асоціації по веденню пацієнтів похилого віку із запальними захворюваннями кишечникаХарченко, Н. В.Ткач, С.М.Дорофєєв, А.Е.Захараш, Н.П.Шатило, В.Б.Скрипник, І.М.Звягінцева, Т.Д.Чижова, В.П.http://localhost:8080/jspui/handle/lib/48302024-01-03T09:40:46Z2022-11-17T00:00:00ZTitle: Клінічні рекомендації Української гастроентерологічної асоціації по веденню пацієнтів похилого віку із запальними захворюваннями кишечника
Authors: Харченко, Н. В.; Ткач, С.М.; Дорофєєв, А.Е.; Захараш, Н.П.; Шатило, В.Б.; Скрипник, І.М.; Звягінцева, Т.Д.; Чижова, В.П.
Abstract: Запальні захворювання кишечника (ЗЗК) у літніх пацієнтів може ускладнювати існуючі супутні захворювання. Фактори ризику ЗЗК у людей похилого віку. Загальні принципи медикаментозної терапії хворих ЗЗК похилого віку. Хірургічні втручання при ЗЗК у похилому віці.2022-11-17T00:00:00ZState of the gut microbiota in patients with metabolic-associated fatty liver disease with type 2 diabetes mellitusDorofeyev, ARudenko, MCheverda, Thttp://localhost:8080/jspui/handle/lib/48112023-11-27T13:02:18Z2022-01-01T00:00:00ZTitle: State of the gut microbiota in patients with metabolic-associated fatty liver disease with type 2 diabetes mellitus
Authors: Dorofeyev, A; Rudenko, M; Cheverda, T
Abstract: One of the frequent complications of the type 2 diabetes mellitus (T2DM) is a metabolic-associated fatty liver disease (MAFLD). Aim. To study the composition of gut microbiota in patients with a combination of T2DM and MAFLD and to compare it with the microbiota in isolated T2DM and MAFLD.
Methods. 111 patients were studied. The main group consisted of 56 patients with a combination of MAFLD and T2DM; the 1st group included 28 patients with MAFLD and the 2nd - 27 patients with T2DM. The control group consisted of 30 practically healthy people. Diagnosis was made by steatometry, shear wave elastography, lactulose H2 breath test, qPCR of feces using primers targeting the 16S rRNA gene, and stool culture.
Results. In the the main group SIBO was found in 48.2%, in 1st – 35.7%, in 2nd – 33.3%, compared to 10% in the control group. When compared wit healthy people, the number of "other" microorganisms significantly increased in the group with isolated T2DM and Clostridium, Proteus and Candida were cultured; in the case of isolated MAFLD, a decrease in Bacteroidetes and an increase in the Firmicutes/Bacteroidetes ratio, as well as an increase in Klebsiella and Clostridium. In the main group, an increase in Actinobacteria, "other" microorganisms, a ratio of Firmicutes/Bacteroidetes and a decrease in Bacteroidetes were found, when cultured - an increase in Clostridium, Klebsiella and Candida.
Conclusions. Only the group of MAFLD with T2DM was characterized by increased Actinobacteria; decreased absolute number of Bifidobacterium and Lactobacillus and increased Escherichia, including with altered enzymatic properties in the stool culture.2022-01-01T00:00:00ZThe dietary treatment of obesityBentsa, TMhttp://localhost:8080/jspui/handle/lib/48102023-11-27T12:47:25Z2023-01-01T00:00:00ZTitle: The dietary treatment of obesity
Authors: Bentsa, TM
Abstract: In the review atricle, an analysis of sources devoted to the issues of dietary therapy of obesity was carried out. Information was sought through internet resources such as PubMed, MedLine, The Cochrane Databases, Google Scholar, Science Direct, Web of Science, and Scopus.
Obesity has reached pandemic proportions worldwide, with more than 1 billion adults overweight (at least 300 million of them are clinically obese) and is a major contributor to the global burden of chronic disease and disability. This is a complex multifactorial disease, in which the accumulated excess fat in the body leads to negative impact on health. The main cause of obesity is a long-term energy imbalance between consumed and expended calories.
Lifestyle modification remains the cornerstone of obesity treatment. An individually selected diet is recommended, which allows you to achieve a state of negative energy balance and is focused on quality food for health promotion. Most often, recommended diets for the treatment of obesity use the following energy restrictions based on changes in the composition of macronutrients: a low-fat diet, a low-carbohydrate and high-fat diet, a low-carbohydrate and high-protein diet, a paleo diet (with a high protein content). Intermittent fasting is considered an alternative to calorie-restricted diets. After an initial period on a high-protein diet, a Mediterranean diet may be an attractive option for continued treatment of obesity, provided that it is given in an energy-restricted form. This diet has been shown to be associated with lower levels of inflammatory biomarkers and metabolic markers of cardiovascular diseases risk.The results of many studies indicate successful weight loss with the help of the Mediterranean diet, not only in the short term, but also in the long term.
For the majority of obese patients, a purposeful change in lifestyle with adherence to the principles of dietary nutrition and regular physical activity allows for effective weight loss, adequate control of metabolic disorders, reduction of the risk of developing concomitant diseases, and long-term maintenance of body weight achieved in the process of losing weight.2023-01-01T00:00:00Z