Allergic contact dermatitis: etiological matrix

Abstract

The article discusses the main links of the pathogenesis of allergic contact dermatitis and gives the results of patch testing in patients who were examined to determine the etiological factors of the disease. Screening showed that nickel, cobalt, methylisothiazolinone, phenylenediamine, formaldehydes and fragrances are the most common etiological factors of ACD. Named haptens cause the absolute majority of positive reactions in the selected group of patients, and also cause the largest number of reactions of pronounced intensity. Patch testing is an informative and useful method for a balanced planning in ACD patients treatment strategy, because it reveals the etiological matrix of the pathological process occurrence in the skin.